The DINAMO study is a prospective cohort study that lasted 30 months, including 18 months of recruitment, in an intensive care unit at a university hospital in Paris, and 12 months of follow-up. During the recruitment period, 100 patients were included, placed on venous-arterial (VA) ECMO for refractory cardiogenic shock and / or cardiac arrest.

ECMO or extracorporeal membrane oxygenation is a last resort technique for extracorporeal assistance to improve oxygenation in the most severe forms of acute respiratory distress syndrome (ARDS), cardiogenic shock or even cardiac arrest. . This assistance allows oxygenation through an extracorporeal membrane and no longer through the lungs.

ECMO can be associated with significant brain injury. However, there is a lack of early neurological prognostic indicators for patients using this system.

The final objective of this observational study was to provide new insights into the pathophysiology and time course of neurological complications in patients under ECMO. But also to help doctors in their daily clinical practice by allowing early identification of neurological complications during ECMO.

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